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International journal of Immunopathology, allergology, infectology.

The importance of oxidative stress and immunological disturbances in vitiligo

Batpenova G.R., Aimoldina A.A., Kotlyarova T.V., Tarkina T.V., Sadykova G.Z., Kazyeva A.S.

Astana Medical University JSC, Astana, Kazakhstan

In this article theories on vitiligo etiopathogenesis, namely, oxidative stress theory and autoimmune theory are considered. The authors present an overview of recent data on the involvement of oxidative stress and immunological disorders in the mechanism of vitiligo development. The focus of the paper is on the latest research to study the changes of cellular and humoral immunity, as well as the imbalance between oxidants and antioxidant protection in vitiligo.

Keywords

Vitiligo, oxidative stress, autoimmune diseases, immunology, reactive oxygen species

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Reference

Batpenova G.R., Aimoldina A.A., Kotlyarova T.V., Tarkina T.V., Sadykova G.Z., Kazyeva A.S. Immunopathology, allergology, infectology 2014; 4:10-14