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International journal of Immunopathology, allergology, infectology.

Nosological structure of acute intestinal infections, endogenous risk factors

Malysh N.G., Doan S.I., Holodilo E.N., Chemych .N., Poddubnay A.I.

1Sumy State University, Sumy, Ukraine
2Main Department of the State Sanitary and Epidemiological Service of Ukraine, Kiev

The nosological structure of diarrheal infections in the north-eastern region of Ukraine is dominated by acute intestinal infection caused by opportunistic pathogens, the weight of which varies between 48.9-58.5 %. Among the etiologic agents prevail K. pneumonia, S. aureus and E. cloacae. Dysbiotic violations of indigenous microflora in intestinal biotope established in 80.0 % of those in the control group and 89.2 % of patients with acute intestinal infections. Significance levels of constancy C. albicans, K. pneumonia, S. aureus and E. cloacae, isolated from the feces of persons of both groups were not statistically different (p> 0.05). The incidence of diseases of the digestive system in patients suffering from acute intestinal infection caused by opportunistic pathogens was higher than in patients with foodborne diseases (p<0.05). Preventing diarrheal infections caused by opportunistic pathogens, it should be fundamentally different from the prevention of the "classic" intestinal infections, and based on knowledge of risk factors for the disease and the ability to manage them.

Keywords

Acute intestinal infections, opportunistic infections, endogenous risk factors, dysbiosis, microbiocenosis, diseases of the digestive system

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Reference

Malysh N.G., Doan S.I., Holodilo E.N., Chemych .N., Poddubnay A.I. Immunopathology, allergology, infectology 2015; 3:40-46