Studying the spectrum of immunotropic action of Pletnev drops No 60 (Phospholiten)
Pletnev V.V., Pinegin B.V.
National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia
The purpose of the present work was studying of immunomodulating activity of Pletnev drops No 60. On the basis of the received results it is established that Pletnev drops No 60 possess immunomodulatory properties, stimulates humoral and cellular immunity, the bactericidal activity of peritoneal exudate cells of mice, bactericidal activity of phagocytes of peripheral blood, promote production of TNF-α by mononuclear cells, the number of peripheral blood leukocytes of mice. Pletnev drops No 60 increase the survival of animals. Pletnev drops No 60 possess antioxidant properties and, under his influence, the observed suppression of spontaneous and simhasan-induced of chemiluminescence of peripheral blood leukocytes of mice and suppression of luminol-dependent and lucigenin-dependent spontaneous and simhasan-induced of chemiluminescence of leukocytes of man.