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International journal of Immunopathology, allergology, infectology.

Using of the immunomodulatory properties of the excimer laser 308nm in therapy of the alopecia areata

Novikov K.A., Tamrazova O.B., Bagramova G.E.

1 Russian scientific center of medical rehabilitation and balneology" of Russian Ministry of Health
2 Russian University Friendship of People Moscow

The etiology of the alopecia areata (A) still remains obscure. According to modern representations, the AA is the autoimmune disease caused by a number of immune, genetic and endocrine factors. First of all, distinguish a koretseptor, the managing CD8+ (CD8 Driven) and T- cells from the factors - regulators reflecting the autoimmune nature of development of AA Th1-type, causing T-cellular autoimmune reaction. Among methods of treatment of AA the most effective is the excimer laser with the wavelength 308nm which influences the main links of pathogenesis and has immunomodulatory effect on the area of an exposition.

Keywords

Laser therapy, alopecia areata, excimer laser 308nm, etiology of alopecia areata, ultra-violet radiation therapy

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Reference

Novikov K.A., Tamrazova O.B., Bagramova G.E. Immunopathology, allergology, infectology 2017; 1:46-51