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International journal of Immunopathology, allergology, infectology.

The role of total serum immunoglobulin E level in diagnosis of fungal allergy

Novikova T.P., Dotsenko E.A.

Belarusian State Medical University, Minsk, Belarus

In the last two decades, there has been an increase in allergic reactions caused by sensitization to fungi. This variant of hypersensitivity causes more severe allergic disease, frequent, prolonged exacerbations that are difficult to control. Therefore, the diagnosis of early stages of fungi allergy is important. The study demonstrates the use of a differentiated model in diagnosis of the allergic nature of a respiratory disease depending on the total serum Ig E level in patients with bronchial asthma and allergic rhinitis with fungi sensitization. A differentiated assessment of total serum Ig E upper normal level, corresponding to clinical respiratory disease manifestations, allows the test using as the first stage of allergy diagnosis: screening of patients with respiratory diseases at the initial appointment to select those patients who need a specific allergy testing, performed by allergologist.


Fungi allergy, immunoglobulin E, bronchial asthma, allergic rhinitis

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Novikova T.P., Dotsenko E.A. Immunopathology, allergology, infectology 2022; 2:58-61. DOI: 10.14427/jipai.2022.2.58