Ectopic taste receptors as a link in the pathogenesis of rheumatological diseases

Melnikova M.A., Mineev V.N., Nesterovich I.I.

Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia

This review is dedicated to the ectopic taste receptors and their role in the pathogenesis of rheumatological diseases.
The purpose of the review is to systematize the available information about taste receptors and their function in the context of the above conditions.
Materials and methods – review of literature sources found in open databases of scientific articles using keywords.
Results – the review examines experimental and clinical data indicating the role of taste receptors in the pathogenesis of rheumatological diseases, primarily their expression and function in various damaged organs, as well as the possibility of use as a therapeutic target.
Conclusions: available sources show the involvement of these receptors in the pathogenesis of various diseases, but for the practical application of the demonstrated results, further research is required both in experimental and clinical settings.