Leukocyte blood cells in the development of an inflammatory response to an allergen in allergic rhinitis

Tahanovich A.D., Kadushkin A.G., Mironova T.V., Makarevich V.V., Shilovskiy I.P., Khaitov M.R.

Belarusian State Medical University, Minsk, Belarus
National Research Center – Institute of Immunology of the Federal Medical-Biological Agency, Moscow, Russia

The article summarizes available data on metabolic and functional changes in T cells, innate lymphoid cells, B cells, natural killer cells, monocytes, dendritic cells, neutrophils, eosinophils and basophils in the blood of patients suffering from allergic rhinitis under the influence of an allergen and allergen-specific immunotherapy. An attempt has been made to present their combined participation in the pathogenesis of this disease, substantiating the prospects for their study for revealing the pathogenesis of allergic rhinitis and assessing the effectiveness of the treatment.