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International journal of Immunopathology, allergology, infectology.

Practice experience of allergen-specific immunotherapy for patients with pollinisis and bronchial asthma

Manina I.V., Ryzhikch A.M., Stas L.I., Dolgina E.N., Slastushenskaya I.E., Trinko V.R., Azizov P.F., Sergeev A.Yu., Karaulov A.V.

We have made the efficiency analysis sublingual and injection ASIT at patients with IgE-dependent diseases. Within 5 years we surveyed 417 person of both sexes, middle age 24,39,8 years. As the basic allergen at 202 persons (48,5% from the general group) was pollen of trees, at 63 patients (15% from group) pollen of cereal grasses, at 71 patients (17% from group) wormwood pollen, at 81 patients (19,5% from group) Dermatofagoidus of a house dust. We have shown good acceptability and safety ASIT. After the first year of treatment efficiency ASIT was 70% of good results and 14% excellent results, and after a complete course treatment has increased to 90% of excellent results.

Keywords

Allergen-specific immunotherapy (ASIT), sublingual allergen, injection allergen, pollinosis, bronchial asthma.

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Reference

Manina I.V., Ryzhikch A.M., Stas L.I., Dolgina E.N., Slastushenskaya I.E., Trinko V.R., Azizov P.F., Sergeev A.Yu., Karaulov A.V. Immunopathology, allergology, infectology 2012; 1:85-92